Everything about Plasmodium Knowlesi totally explained
Plasmodium knowlesi is a
primate malaria parasite commonly found in
Southeast Asia. It causes malaria in long-tailed macaques (
Macaca fascicularis), but it may also infect humans, either naturally or artificially.
Epidemiology
Reports of human
P. knowlesi infections are confined to Southeast Asia, particularly Malaysia, but there are also reports on the Thai-Burmese border. A fifth of the cases of malaria diagnosed in
Sarawak,
Malaysian Borneo are due to
P. knowlesi..
Within the monkey population in Peninsular Malaysia, A. hackeri
,
is believed to be the main vector of 'P. knowlesi' :
although 'A. hackeri'
is capable of transmitting malaria to humans,
it isn't normally attracted to humans and therefore can't be an important vector for transmission.
Diagnosis
P. knowlesi infections is diagnosed by examining thick and thin blood films in the same way as other
malarias. The appearance of
P. knowlesi is similar to that of
P. malariae and is unlikely to be correctly diagnosed except by using molecular detection assays in a malaria reference laboratory. There are no ill effects of misdiagnosing
P. knowlesi as
P. malariae, because the treatment is the same.
This article
says that knowlesi infections should be treated with more intensive medication.
Treatment
P. knowlesi infection responds well to treatment with
chloroquine and
primaquine.
Plasmodium knowlesi genome data
Further Information
Get more info on 'Plasmodium Knowlesi'.
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